Cardarine (GW 501516) Review, Dosage Guide, Side Effects and Results


Obtaining a lean physique is a goal of most people who get into fitness. Unfortunately, slimming down can be tough. Losing those last few pounds of body fat can be one of the most challenging aspects of obtaining your goals.

Luckily, there have been many scientific breakthroughs in the realm of dieting.

Cardarine, also known as GW 501516, is a promising new compound that may be able to help you achieve a better body. It’s been circulating a lot around bodybuilding communities and has made its way into the mainstream over the last year as well.

Today we are going to look at how cardarine works, some of it’s benefits, side effects, and provide a dosing guide.

How Cardarine Works

People often confuse cardarine as being a SARM. This is not correct, and it does not affect hormones. In fact, GW-501516 is a PPAR agonist.

PPAR agonists like GW501516 help the body get rid of the brown adipose fat tissue in the body. For men and women, this type of fat likes to hang out in the belly, thighs, and hip areas.

In fact, cardarine is currently being studied as a cure for obesity. More on that below.

Benefits of Using Cardarine

There are countless benefits of using GW501516 in your supplement regimen. Some of these benefits include fat loss, increased endurance, more stamina, and lower cholesterol levels. Let’s take a look at some of the benefits in detail.

Lowered Body Fat

The main reason that people gravitate to this compound is it’s ability to lower body fat.

Cardarine is incredibly effective at helping the body utilize fat storage as energy. In studies, cardarine was shown to decrease bodyfat percentages in every participant. This result happened with no changes to diet or exercise levels.

Decreased Muscle Wasting

One of the worst part about going on a cut is losing muscle. What’s the point of losing 20lbs if you end up looking skinny and frail when you’re done? Cardarine shines here, and can prevent muscle wasting from occuring.

When you incorporate GW501516 into your cut, you will be able to cut more calories and lose less muscle.

Increased Endurance

One of the most fascinating aspects of cardarine is it’s ability to increase aerobic endurace. People taking GW 501516 will have the ability to perform exercise at a longer time with less fatigue. For distance runners, power athletes, or anyone who needs that extra push, this is huge.

The increased endurance levels will help you train longer, harder, and experience less fatigue. This of course provides better results from your training regimen whether bulking or cutting.

cardarine bottles

Cardarine Side Effects

Like all good things in life, GW 501516 does have some side effects. In fact, this product was discontinued by it’s manufacturer over a cancer scare. Let’s address that first.

The study in question showed that rats given large amounts of GW-501516 had increased levels of cancer growth. The growth was in tumors that already existed in the rats, but is nevertheless scary.

The cancer growth seems to comes from an increase of  Angiogenesis. This is also common in endurance athletes who do not take supplements at all.

Another thing to mention is that the amount of GW given to the rats in the study was upwards of 400mg a day. This dose was provided for a long period of time. Keep in mind, most humans will take a dose of 20mg a day for no longer than 12 weeks at a time.

With all the facts on the table, we feel comfortable using this compound in our supplement regimen. As with everything in life, do your homework and use your best judgement.

Where to Buy Cardarine

Finding a reputable source of cardarine online can be tricky. With the approaching sarms ban, a lot of companies have stopped selling it.

Another big thing to consider is purity. Unfortunately, a lot of companies are selling either bunk (fake) product. It’s very importatnt to make sure the company you are buying from provides 3rd party lab results.

We have tried and tested the GW 501516 from Proven Peptides and are able to say that it is legit. PP is the best choice for people in the USA at the moment. If you’re in Europe, Sarms4You can be a good option as well.

What is the Best Dosage for Cardarine?

We’ve found that the best dosage to be 20mg per day, for up to 12 weeks. This is the same whether you are using it to bulk, cut, or recomp. Some users even find results at 10mg a day, so you can follow that protocal as well if you find it more appealing.

Half life

The half life of cardarine is reported to be between 16 to 24 hours. With that being said, twice daily dosing is always recommended by me. I’ve found that peak plasma levels stay a lot more in sync when dosing twice per day.

Stacking Cardarine With Other SARMs

If you’re serious about achieving your goal physique, you might want to look into stacking with product with other SARMs. By itself, cardarine is incredibly mild. While it is a great “polishing agent” for losing that last bit of body fat, it really shines when part of a stack.

For Bulking

Use GW 501516 in combination with ligandrol to keep your bulk lean and not gain any body fat. Here is an example:

  • LGD 4033 at 10mg per day and GW 501516 at 20mg for 8 weeks
  • GW501516 for 20mg 4 weeks after that

For Cutting

This combo will really let your physique shine. Try this for losing fat and preserving muscle:

  • Ostarine 20mg per day for 12 weeks AND
  • Cardarine 20mg per day for 12 weeks

cardarine results

What Results to Expect

People taking cardarine can expect to lose around 10lbs of body fat over 8 to 12 weeks. Of course, diet and exercise is key here. If you combine the two with this compound you WILL lose weight quickly and effectively.

If you are using it to bulk or recomp, you can expect leaner gains with increased endurance.

Some Commonly Asked Questions

We get a lot of questions about GW 501516. We’ve compiled a list to assist you. If you have any other questions, make a post in the comments below and we will update this list.

Will cardarine be banned?

While the upcoming sarms ban may not include GW 501516 specifically, a lot of retailers will get shut down. Expect this compound to become harder to source over the next coming months.

Can cardarine cause gyno?

NO! If you are getting gynocomastia from GW, then your product is bunk.

Can you tak cardarine at night?

Yes, there are no issues taking it at night. It will help burn fat while you sleep.

Can females take cardarine?

Yes, there are no issues with females taking cardarine. It is non hormonal and there are no risks of viralization.

Do you need a PCT?

As mentioned above, it is not hormonal, so a PCT is not required. However, if you take it with ostarine or LGD, you might want to consider it.

Final Thoughts and Conclusion

With all that being said, this is a great product for anyone who wants to get a better body. GW will help you burn fat, retain muscle, and even lower bad cholesterol levels. As with everything, talk to your doctor before starting any PPAR agonist. We hope you enjoyed our guide!


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